Posts Tagged ‘CTN-0018’

CPDD Poster from PN Node Researchers

June 27, 2011

CTN Pacific Northwest Node researchers Mary Hatch-Maillette, Don Calsyn, Blair Beadnell, and Lynette Wright, along with colleagues Ann Burlew and Jerika Wilson from the Ohio Valley Node, recently presented a poster at the College on Problems of Drug Dependence (CPDD) annual meeting in Hollywood, FL, June 18-23, 2011.

The poster, entitled “Culturally Tailoring the Real Men Are Safe HIV Prevention Intervention,” reported on the early stages of a study designed to revise the CDC recognized, evidence-based REMAS prevention intervention to make it more culturally relevant to African American and Hispanic men, and then conduct a pilot feasibility trials of the revised REMAS in four CTN CTPs.

The manual was revised using the “Delphi Process,” with expert panel members reviewing,  rating, and offering specific suggestions of improvements for all the modules in two separate rounds.  The panel members’ quantitative ratings and qualitative suggestions were, for the most part, consistent with each other, with the qualitative feedback being used more extensively in making revisions to REMAS. 

The Delphi Process was found to be a successful technique, and the effectiveness of the REMAS-CA (Culturally Adapted) is currently undergoing pilot testing.

Citation:  Hatch-Maillette MA, Calsyn DA, Burlew AK, Wilson J, Beadnell B, Wright L.  Culturally Tailoring the Real Men Are Safe HIV Prevention Intervention.  Poster presented at the College on Problems of Drug Dependence (CPDD) annual meeting, Hollywood, FL, June 18-23, 2011.  Find it in the CTN Dissemination Library!


Sexual Risk Behavior and Sex Under the Influence

March 29, 2011

This in-press article at American Journal on Addictions, by Don Calsyn and Mary Hatch-Maillette of the Pacific Northwest Node and colleagues, looked at a small subset of participants from protocol CTN-0018 to determine if there was evidence of a causative link between sex under the influence of drugs or alcohol and risky sex for men in substance abuse treatment.  In this high risk sample, a causative link between sex under the influence and risky sexual behavior was not supported.

These findings reinforce the hypothesis that sex under the influences needs to be treated primarily as a relapse prevention issue, rather than an HIV/STD prevention issue.

Citation: Calsyn DA, Baldwin H, Niu X, Crits-Christoph P, Hatch-Maillette MA.  Sexual Risk Behavior and Sex Under the Influence: An Event Analysis of Men in Substance Abuse Treatment Who Have Sex with Women.  American Journal on Addictions 2011 (in press).  Find it in the CTN Dissemination Library.

Teaching Condom Use Skills

November 1, 2010

The latest paper from protocol CTN-0018  by PNW Node researchers Donald Calsyn, Mary Hatch-Maillette, and Suzanne Doyle, as well as other colleagues from the project, was just published in the journal Substance Abuse.

The article, “Teaching Condom Use Skills:  Practice is Superior to Observation,” found that men participating in the study could effectively be taught correct male and female condom use skills using an interactive skills practice exercise, and maintain those skills for up to six months.  Participants only exposed to a demonstration of condom skills, or who received no intervention at all, did not perform as well.

Learn more about the study in the CTN Dissemination Library:

Two CTN-Related Articles from the PNW Node Now Free at PubMed Central

September 1, 2010

Nearly every month, a new set of articles from the National Drug Abuse Treatment Clinical Trials Network (CTN) are made available for free, full-text, in PubMed Central, as per the NIH Public Access Policy, which requires all NIH-funded research be made freely available within a year of  publication.

Two articles written by authors from the Pacific Northwest Node have joined the list of free articles in PubMed Central this month:

Motivational and Skills Training HIV/Sexually Transmitted Infection Sexual Risk Reduction Groups for Men — Calsyn DA, Hatch-Maillette MA, Tross S, et al. Journal of Substance Abuse Treatment 2009;37:138-150.

This paper presents the primary outcomes of CTN-0018, which evaluated the effectiveness of a motivational and skills training HIV/AIDS group intervention for men in substance abuse treatment, finding it more effective in reducing sexual risk than a standard, one-hour HIV education session.

Agency Context and Tailored Training in Technology Transfer: A Pilot Evaluation of Motivational Interviewing Training for Community Counselors — Baer SJ, Wells EA, Rosengren DA, et al. Journal of Substance Abuse Treatment 2009;37(2):191-202.

This study evaluated a context-tailored training model that used standardized patient actors and role-play to determine if such a technique is effective in training counselors in new evidence-based practices (here, motivational interviewing). Outcomes suggest tailored training methods may not produce better results than traditional workshops.

Substance Use and HIV Research Symposium

August 23, 2010

The University of Washington Center for AIDS Research (CFAR) is sponsoring a symposium entitled “Substance Use and HIV Research.”

When: Thursday, August 26, 2010, 10:30am to 12:30pm
Where: UW Parrington Hall Forum, Room 309 (see map)

David Metzger, PhD of the University of Pennsylvania HIV Prevention Research Division will give a presentation entitled “Drug Treatment is HIV Prevention.” Alcohol & Drug Abuse Institute researcher Don Calsyn, PhD, will be talking about “Conducting HIV Prevention Interventions in Substance Abuse Treatment,” describing his National Drug Abuse Treatment Clinical Trials Network (CTN) protocol, CTN-0018, “Reducing HIV/STD Risk Behaviors: A Research Study for Men in Drug Abuse Treatment.”

View the flyer for this symposium.

For more information, please contact Kate Murray at, or 206-543-8316.

Men in Methadone Maintenance versus Psychosocial Outpatient Treatment: Differences in Sexual Risk Behaviors and Intervention Effectiveness from a Multisite HIV Prevention Intervention Trial.

July 29, 2010

This new article in Journal of Addictive Diseases, written by Don Calsyn, Susan Doyle, and Mary Hatch-Maillette of the Alcohol & Drug Abuse Institute at the University of Washington, as well as other colleagues from the National Drug Abuse Treatment Clinical Trials Network (CTN), reports on the effectiveness of the Real Men Are Safe (REMAS) HIV prevention intervention (protocol CTN-0018) as a function of treatment program modality.

REMAS is a five-session sexual risk reduction intervention for men involving didactically delivered informational material, role playing, peer group discussions, and self-assessment motivational exercises (see REMAS manual).

REMAS was associated with significantly larger decreases in unprotected sexual occasions than an HIV education control condition in both methadone maintenance and psychosocial outpatient program participants, however it was especially effective with the latter group.  Potential reasons why are explored in this article, including differences in patient variables, the effects of methadone as a treatment, and greater relevance of the REMAS intervention to patients in outpatient treatment.

Modifications of the REMAS approach may be needed to further enhance effectiveness with methadone maintained patients.

Find the article in the CTN Dissemination Library:

Article citation: Calsyn DA, Campbell ANC, Crits-Christoph P, Doyle SR, Tross S, Hatch-Maillette MA, Mandler RN.  Men in methadone maintenance versus psychosocial outpatient treatment: Differences in sexual risk behaviors and intervention effectiveness from a multisite HIV prevention intervention trial.  Journal of Addictive Diseases 2010;29(3):370-382. [doi: 10.1080/10550887.2010.489451]

Reducing Sex Under the Influence of Drugs or Alcohol for Patients in Substance Abuse Treatment.

January 7, 2010

In a previous report (Calsyn et al, 2009), the effectiveness of the Real Men Are Safe (REMAS) intervention in reducing the number of occasions of unprotected sex among male patients in drug abuse treatment was demonstrated. A secondary aim of REMAS was to reduce the frequency with which men engage in sex while under the influence (SUI) of drugs or alcohol.

This new article in the journal Addiction, written by Pacific Northwest Node researchers Donald Calsyn, Mary Hatch-Maillette, and Suzanne Doyle, as well as other CTN colleagues, reports the outcomes of that secondary aim, finding that REMAS, an intensive skills-based HIV prevention intervention, was indeed associated with greater reduction in the frequency of SUI among men in substance abuse treatment compared to standard HIV education at the 3-month follow-up.

Read more about this article in the CTN Dissemination Library.

Citation: Calsyn DA, Crits-Christoph P, Hatch-Maillette MA, Doyle SR, Song YS, Coyer S, Pelta S. Reducing sex under the influence of drugs or alcohol for patients in substance abuse treatment. Addiction 2010;105(1):100-108. [doi: 10.1111/j.1360-0443.2009.02812.x]

Sexual Risk Reduction for Men and Women in Substance Abuse Treatment: New CTN Manuals Published

October 28, 2009

Two CTN studies involving researchers and community treatment providers in the Pacific NW Node, in conjunction with programs in other states, have produced manuals that guide clinicians in the implementation of evidence-based interventions for reducing sexual risk behavior among men and women in substance abuse treatment.  Evergreen Treatment Services (Seattle) participated in both studies.

Don Calsyn, PhD (ADAI) was the lead investigator for CTN-0018, Reducing HIV/STD Risk Behaviors: A Research Study for Men in Drug Abuse Treatment.  The manual Real Men Are Safe (REMAS): A Gender-Focused HIV and Sexual Risk Reduction Intervention for Men in Substance Abuse Treatment is a five-session, group-delivered intervention package designed to help clients in substance abuse treatment reduce their HIV risk.  Outcomes from CTN-0018 found that the this motivational and skills training HIV intervention was associated with greater sexual risk reduction than a standard HIV education session, suggesting that substance abuse treatment programs can help reduce sexual risk among their patients by providing not only information, but also practice skills.

Directed by Susan Tross, PhD in New York, CTN-0019 led to the development of the manual, Safer Sex Skills Building: A Manual for HIV/STD Safer Sex Skills Groups for Women in Outpatient Substance Abuse Treatment.  This is also a five-session intervention package, focusing on the importance of changing high-risk behaviors and teaching women the social and technical skills necessary to keep them from engaging in these high-risk behaviors, including skills intended to help women protect themselves from partner abuse as the potential result of assertiveness around safer sex.

The manuals were formatted for publication by CTN Dissemination Librarian Meg Brunner (PN Node), and are now available to download for free from the Library’s web site. The manuals come with slides for flip charts used in the interventions, and a participants’ workbook is provided with the women’s manual. Questions about either manual may be directed to the developers.

Factor Structure of the Condoms Barriers Scale

September 4, 2009

This article in the journal Assessment was written by Pacific Northwest node members Suzanne R. Doyle, PhD, and Donald A. Calsyn, PhD, along with Samuel A. Ball, PhD from the New England node.

It assesses the psychometric properties of the Condom Barriers Scale (CBS), an instrument originally designed to measure women’s perceptions and attitudes regarding male condom use, with a sample of men at high risk for HIV.  Participants included 590 male patients involved in protocol CTN-0018.

Overall, the analysis indicated that the CBS is a potentially valid and reliable instrument with utility for assessing barriers to condom use with men, but may need some item content modifications to allow appropriate assessment of gender differences and comparisons across studies.

Citation: Doyle SR, Calsyn DA, Ball SA.  Factor structure of the Condom Barriers Scale with a sample of men at high risk for HIV.  Assessment 2009;16(1):3-15 [doi: 10.1177/1073191108322259].

Read more about this article in the CTN Dissemination Library.