Archive for January, 2013

Patient Characteristics Related to Treatment Outcome: More from POATS

January 24, 2013

Currently in-press at Drug and Alcohol Dependence, this article by Jessica Dreyfuss, Margaret Griffin, Katherine Frost, and colleagues from the New England Consortium and Greater New York Nodes, as well as Mary Hatch-Maillette, PhD of the Pacific Northwest Node, reports on a secondary analysis of data from protocol CTN-0030 (Prescription Opioid Addiction Treatment Study (POATS)) examining patient characteristics that predict treatment outcome.

Baseline characteristics of 360 patients participating in the study were assessed. In bivariate analyses, pre-treatment characteristics associated with successful opioid use outcome included older age, past-year or lifetime diagnosis of major depressive disorder, initially obtaining opioids with a medical prescription to relieve pain, having only used opioids by swallowing or sublingual administration, never having used heroin, using an opioid other than extended-release oxycodone most frequently, and no prior opioid dependence treatment. In multivariate analysis, age, lifetime major depressive disorder, having only used opioids by swallowing or sublingual administration, and receiving no prior opioid dependence treatment remained as significant predictors of successful outcome.

This is the first study to examine characteristics associated with treatment outcome in patients dependent exclusively on prescription opioids. It is hoped that knowledge about patient characteristics associated with successful (and unsuccessful) outcome from the current study can be used to help develop more effective treatments for this patient population.

Citation: Dreifuss JA, Griffin ML, Frost K, et al. Patient Characteristics Associated with Buprenorphine/Naloxone Treatment Outcome for Prescription Opioid Dependence: Results from a Multisite Study. Drug and Alcohol Dependence 2013 (in press).


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Ron Jackson, Executive Director of Evergreen Treatment Services, Retires

January 18, 2013
Newly retired Mr. Jackson has plans to take up the ukelele and travel to Hawaii as much as possible!

Ron has plans to take up the ukelele and travel to Hawaii!

After 33 years as the Executive Director of Evergreen Treatment Services, a long-time CTP in the Pacific Northwest Node of the CTN, Ron Jackson, MSW, LICSW, officially retired from that position on January 13, 2013.

He will continue in a part-time role at ETS, helping with the REACH Program, which includes the Law Enforcement Assisted Diversion (LEAD) Project and with the potential establishment of new clinics.  Ron will also retain his faculty position at the University of Washington’s School of Social Work. Over many years, Ron collaborated with UW researchers on numerous projects, most recently on NIDA’s National Drug Treatment Clinical Trials Network (CTN) where he represented community treatment programs on the CTN Executive Committee.

Ron’s successor at ETS is Molly Carney, PhD.  Dr. Carney received her doctorate in Clinical Psychology from the University of Washington and worked in Alan Marlatt’s Addictive Behaviors Research Center before moving to the UW Alcohol and Drug Abuse Institute.  She left ADAI in 2006 to complete her MBA at the UW Foster School of Business in 2007.  Last year, Dr. Carney came to work with Ron at ETS where they’ve spent the past 18 months together preparing for this transition.

A retirement party for Ron was held on Friday, January 11th and featured dozens of his staff and colleagues, past and present, many of whom gave brief speeches praising Ron’s professionalism, dedication to service, and decades of hard work balanced with a generous and good-natured spirit.

A set of wonderful photographs from this event, taken by photographer Jarett Kaplan, can be found at this URL: https://picasaweb.google.com/104124588174141071416/RonJacksonRetirementParty1112013?authuser=0&authkey=Gv1sRgCJ33uYPIz6XrYg&feat=directlink

Best of luck to you, Mr. Jackson, in this new chapter of your life! We will miss you very much here at ADAI!

 

From STAGE-12: Impulsivity Associated with Treatment Non-Compliance in Stimulant-Dependent Patients

January 14, 2013

This ancillary investigation of data from the STAGE-12 protocol (CTN-0031), currently in-press in Journal of Substance Abuse Treatment and co-written by Theresa Winhusen, Daniel Lewis, Bryon Adinoff, and colleagues Dennis Donovan and Jessica DiCenzo from the Pacific Northwest Node, among others, evaluated the relationships among impulsivity, stimulant-dependence diagnosis, and treatment completion.

Six sites from CTN-0031 obtained BIS-11 and Stroop Color Word test results from 182 methamphetamine- and/or cocaine-dependent participants. Methamphetamine-dependent, relative to cocaine-dependent, participants evidenced significantly greater BIS-11 non-planning and total scores. Accounting for other factors related to treatment completion, BIS-11 motor score, and assessing the tendency to act without thinking predicted treatment completion for both cocaine-dependent and methamphetamine-dependent patients.

Conclusions: These results suggest that methamphetamine-dependent and cocaine-dependent patients may have different impulsivity profiles but that the BIS-11 may be useful in identifying both methamphetamine-dependent and cocaine-dependent patients who are at risk for treatment non-completion.

Citation: Winhusen TM, Lewis DF, Adinoff BH, et al. Impulsivity is Associated with Treatment Non-Completion in Cocaine- and Methamphetamine-Dependent Patients but Differs in Nature as a Function of Stimulant-Dependence Diagnosis. Journal of Substance Abuse Treatment 2013 (in press).


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Workshop on “Evidence-Informed Management of Co-Occurring Addiction & Mental Illness in Adults and Adolescents,” Feb 8 in Spokane

January 10, 2013

TreeThe Pacific Northwest Node of  the National Drug Abuse Treatment Clinical Trials Network will host a 1-day training in Spokane, WA for professionals who want to improve their own or their agency’s competence in assessing, managing, and treating patients with co-occurring substance use disorders and mental illness.

The format will include both lectures and interactive discussions of case studies, covering content presented in the June 2012 workshop held in Seattle, with an additional focus on adolescents.

Speakers will include:  Richard K. Ries, MD (UW and Harborview Medical Center), Matt Layton, MD, PhD (WSU), and Ray Hsiao, MD (UW and Seattle Children’s Hospital).

This training is FREE, but registration is required and space is limited. CEUs from NAADAC and NBCC are also available for free!  A limited number of travel awards will be available for individuals traveling from rural and/or under-represented areas in Eastern Washington or Northern Idaho.  (To apply for a travel award, contact Sharon Falk at falk@wsu.edu.)

When: Friday, February 8, from 9:00am  to 4:00pm
Where:  South Campus Facility, WSU Spokane campus
Registrationhttp://tinyurl.com/CTN-PNW-Training2013

This program is supported by the CTN Pacific Northwest Node at the UW Alcohol & Drug Abuse Institute, Washington State University-Spokane, NW Addiction Technology Transfer Center, and Daybreak Youth Services.