Archive for August, 2011

Combined Group and Individual 12-Step Intervention (STAGE-12)

August 31, 2011

journal coverThis paper, newly published in the Journal of Groups in Addiction and Recovery (written by Dennis Daley, Stuart Baker, Dennis Donovan, and colleagues), provides an introduction to  protocol CTN-0031, a multi-site clinical trial of a behavioral intervention for outpatients with stimulant use disorders.  The Pacific Northwest Node is the Lead Node for this protocol, with CTPs Evergreen Manor and Recovery Centers of King County serving as clinical sites.

The article describes the study’s adaptation of a combined individual and group intervention aiming to facilitate patients’ involvement in 12-step mutual support programs, along with a review of the questions that came up during the protocol’s development, outcomes of the intervention, and why 12-step counseling approaches should be considered for a multi-site trial.

The paper emphasizes the importance of bidirectional collaboration between researchers and treatment providers, and shows evidence of how CTPs participate in all phases of a trial, from identifying an important clinical area for research, through protocol development and implementation.  Results of the study’s data analysis will be presented in a future paper.

Citation: Daley DC, Baker S, Donovan DM, Hodgkins CC, Perl HI.  A Combined Group and Individual 12-Step Facilitative Intervention Targeting Stimulant Abuse in the NIDA Clinical Trials Network: STAGE-12.  Journal of Groups in Addiction and Recovery 2011;6(3):228-244.

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Find it in the CTN Dissemination Library!


CTN Special Issue of American Journal of Drug and Alcohol Abuse

August 25, 2011

The greatly anticipated special CTN issue of American Journal of Drug and Alcohol Abuse (2011, v. 37(5)) is now available online!  The issue brings together articles that reflect 12 years of experience in the National Drug Abuse Treatment Clinical Trials Network (CTN), with methodological and statistical issues that arise in the design and conduct of controlled, multi-site, community-based effectiveness trials. To date, the CTN has randomized over 13,000 patients into 27 completed trials, with more trials currently ongoing, providing a wealth of experience in design, implementation, and analysis of effectiveness trials.

This issue features a broad spectrum of CTN ancillary investigations, lessons learned, and ideas for the future, many co-written by or involving the work of researchers and counselors from the Pacific Northwest Node.

Find all the articles from the special CTN issue in the CTN Dissemination Library (where you can read the abstracts and request copies of the full articles you are interested in from the CTN Dissemination Librarians!):

And congratulations to all the researchers, counselors, statisticians, and more whose hard work in the CTN is featured in the issue!

CTN-0018 and CTN-0019 Highlighted in NIDA Notes

August 12, 2011

An article in the new issue of NIDA Notes highlights the outcomes of CTN-0018,  and CTN-0019, both of which involved the Pacific Northwest Node (CTN-0018 was led by our node and researcher Don Calsyn, and Evergreen Treatment Services participated in both protocols).

In a large-scale test of gender-specific interventions, male participants in CTN-0018’s  Real Men Are Safe (REMAS) and female participants in CTN-0019’s Safer Sex Skills Building (SSB) workshops made greater reductions in high-risk sexual behavior for a longer period than comparison groups, who were provided a standardized single-session HIV educational intervention designed to mimic those provided in many substance abuse clinics. Moreover, at the 3-month followup, men who received the training were less likely than the comparison group to have been under the influence of drugs during their most recent sexual experience.

For detailed descriptions of the interventions and free manuals and implementation aids regarding REMAS, see; for SSB, see

Citation:  Bonetta L. Intensive Interventions Reduce Risky Sexual Behaviors. NIDA Notes 2011;23(5):10-11.  Find it in the CTN Dissemination Library!